Lesley or Leslie may refer to:
General Hospital characters[]
- Lesley Lu Spencer - Full name of Lulu Spencer.
- Lesley Webber - Doctor and estranged widow of Rick Webber, mother of Laura Webber and adopted Mike Webber.
Actresses[]
- Leslie Charleson - The actress who portrays Dr. Monica Quartermaine (1977-2022, 2023-present).
- Leslie Horan - The actress who portrayed Miranda Jameson (1996-97).