She has been portrayed by actress Chloe Lanier since the character's debut on August 8, 2016.
On July 12, 2016, ABC Soaps In Depth broke the news that Chloe Lanier would return to General Hospital in a brand new contract role. Lanier, a familiar face on the soap, was known for her popular portrayal of teenage Pat Spencer for two episodes on April 1, 2015 and on July 23, 2015.
General Hospital was very "tight-lipped" about "Nelle's" character and her Port Charles connections to allow the mystery to unveil overtime.
Due to the actress's former role, there has been speculation that Nelle could be the previously unknown daughter of Pat Spencer and half-sister of Valerie Spencer, making her a member of the Spencer family. However, her connections and identity are still unknown.
Carly had been conned for her money before, so Jax and Sonny were hesitant to believe Nelle's story, thinking she was just another person after the money. Nelle shows them her scar and tells them that her parents sold her kidney when she was a child. Nelle's story and the dates matched up with Josslyn's transplant, but they all want to be sure, so they go to General Hospital to run some tests. Nelle meets Josslyn and the two briefly bond. She is happy to see that the ordeal she went through ended up saving a little girl's life. Preliminary blood tests confirmed that Nelle was a match to Josslyn, but to be certain, Dr. Monica Quartermaine recommended a kidney biopsy. However, Sonny explained it wasn't necessary because he located the clinic where Nelle had her surgery, and the timeline worked out.
This information along with the matching blood tests led everyone to believe that Nelle was Josslyn's donor. Josslyn was upset when she realized that her mother had ignored her wishes about finding the kidney donor, but took an instant liking to Nelle and thanked her for the gift of life. Nelle promised she had no regrets, but she had to get back to Atlanta. Carly asked Nelle to stay because she wanted a chance to get to know her and she agreed. After Avery Jerome-Corinthos's nanny was caught stealing Carly's earrings, Carly fired the nanny and offered the job to Nelle. Having just lost her job in Atlanta, she agreed to watch Avery. Nelle lost this position when Carly's mother, Bobbie offered to be Avery's nanny. Bobbie also appeared suspicious of Nelle. Not wanting Nelle to leave, Carly offered her a job at the Metro Court Hotel as her personal assistant and Nelle accepted.
On November 23, Nelle saw Carly and Jax kissing. She went right over to Sonny's to tell him. On November 28, Nelle drugged Sonny, and he passed out. Nelle helped get him into bed, undressed him and, then apologized, before undressing herself. She climbed into bed beside him. On November 29, Sonny woke up and believed he and Nelle slept together. He begged Nelle not to tell Carly, but in November, it was revealed that Nelle had recorded Sonny mentioning that they slept together.